組織相容性复合物相關蛋白MR1抗體
產品名称： 組織相容性复合物相關蛋(dan)白MR1抗體
英文名称： MR1
產品编號： bs-17747R
產品价格： null
產品產地： 北京
品牌商標： BIOSS
更新時間： 2026-09-21T09:09:58
使用範围： WB=1:100-500,ELISA=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,
北京(jing)郭惠彩科技(ji)有限公司
- 聯系人 : 郭惠彩-龚思雨
- 地址 : 北京市北京經濟技術開(kai)发區環科中路16號26幢3層301
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MR1 is a 341 amino acid single-pass membrane protein that localizes to the endoplasmic reticulum, as well as to the extracellular side of the cell membrane, and contains one Ig-like C1-type domain. Expressed ubiquitously, MR1 exists as a heterodimer with β-2-Microglobulin and plays an important role in antigen presentation, specifically in the development and expansion of mucosal-associated invariant T cells (MAITs). MAITs are located in the gut and are involved in monitoring flora levels, as well as in conveying distress signals to other areas of the body, indicating a role for MR1 in proper digestion and immune system function. MR1 exists as four alternatively spliced isoforms and is encoded by a gene which maps to human chromosome 1.