Anti-Active Rab5 Mouse Monoclonal Antibody
Anti-Active Rab5 Mouse Monoclonal Antibody是一(yi)款针對活性Rab5蛋白的小鼠單克隆(long)抗體(ti)產品，專(zhuan)門用
Anti-Active Rab5 Mouse Monoclonal Antibody 是(shi)一種针對活性 Rab5 蛋白的小鼠單克隆(long)抗體(ti)產品。
產品编號： 26911
產品价格： null
產品產地： 美國
品牌商標： NewEastbio
更新時間： null
使用範围： IP, IHC
武(wu)漢纽斯特生物技術(shu)有限公司
- 聯系人 :
- 地址 : 武漢市东湖(hu)新技術開发區光谷生物(wu)城B3-3栋2-3楼
- 郵编 : 430074
- 所在區域 : 湖北
- 電話 : 186****7297 點擊查看
- 傳真 : 點擊查看
- 郵箱 : [email protected]
| Catalog Number: 26911 |
| Gene Symbol: RAB5 |
| Description: Anti-Active Rab5 Mouse Monoclonal Antibody |
| Background: Rab5 is a member of Rab-family GTPases. Rab5 is a rate-limiting component of the machinery regulating the kinetics of membrane traffic in the early endocytic pathway. |
| Immunogen: Recombinant full length protein of active Gao |
| Applications: IP, IHC |
| Recommended Dilutions: 1 µg for ~2 mg total cellular proteins for IP 1:100 dilution for IHC |
| Concentration: 1 mg/ml |
| Host: mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: IgG1 |
| Purity: Purified from ascites |
| Storage buffer: |
| Preservative: no |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Anti-active Rab5 antibody recognizes active Rab5 proteins of vertebrates. |
| Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles |
| Immunoprecipitation/Western blot: |
|
Rab5 activation assay. Purified full-length Rab5A proteins were immunoprecipitated after treated with GDP (lane 1) or GTPγS (lane 2). Immunoprecipitation was done with the anti-active Rab5 monoclonal antibody (Cat. No. 26911). Immunoblot was with an anti-Rab5 polyclonal antibody (Cat. No. 21151). |
| Publications: |
| 1. VASP promotes TGF-β activation of hepatic stellate cells by regulating Rab11 dependent plasma membrane targeting of TGF-β receptors Hepatology Volume 61, Issue 1, pages 361–374, January 2015 |
| 2. Rab5 Activity Regulates GLUT4 Sorting into Insulin-Responsive and Non-Insulin-Responsive Endosomal Compartments: A Potential Mechanism for Development of Insulin Resistance Endocrinology. 2014 Sep;155(9):3315-28 |